Investigating how vaping during pregnancy affects children's lung health

ENDS aerosol particle deposition, in utero exposures and children's respiratory health effects (ENDURE)

NIH-funded research Trustees of Indiana University · NIH-11021725

This study is looking at how using e-cigarettes while pregnant might affect the lung health of children, so if you're a mom who uses these products or is around them, your experience could help us understand the long-term effects on kids' breathing.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionTrustees of Indiana University NIH-funded
Lab location1 site (Bloomington, United States)
Project IDNIH-11021725 on NIH RePORTER

What this research studies

This research examines the impact of in utero exposure to electronic nicotine delivery systems (ENDS), such as e-cigarettes, on the respiratory health of children. By analyzing how aerosol particles from these products deposit in the lungs of pregnant women and their potential effects on fetal lung development, the study aims to understand the long-term respiratory outcomes for children. The research involves collaboration among multiple institutions to gather comprehensive data on this important public health issue. Participants may include mothers who use ENDS products or are exposed to ENDS aerosols in their environment.

Who could benefit from this research

Good fit: Ideal candidates for participation include pregnant women who use e-cigarettes or are exposed to e-cigarette aerosols.

Not a fit: Patients who do not use ENDS products and are not exposed to ENDS aerosols may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved understanding and prevention strategies for respiratory issues in children exposed to vaping during pregnancy.

How similar studies have performed: While research on the effects of traditional tobacco exposure during pregnancy is established, the specific impacts of ENDS exposure are still being explored, making this a novel area of investigation.

Where this research is happening

Bloomington, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.