Investigating how vaginal bacteria affect preterm birth in women with HIV
Vaginal Microbiome and Metabolites in Preterm Birth
This study is looking at how the bacteria in the vagina might affect the risk of early delivery in women with HIV, hoping to find ways to help improve pregnancy outcomes for these women.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project ID | NIH-10893465 on NIH RePORTER |
What this research studies
This research focuses on understanding the role of the vaginal microbiome in preterm birth among women living with HIV. It aims to explore how changes in vaginal bacteria, particularly bacterial vaginosis, can increase the risk of delivering before 37 weeks of pregnancy. The study will involve analyzing the vaginal microbiome and its metabolites to identify potential inflammatory pathways that contribute to preterm birth. By integrating clinical experience with microbiome research, the project seeks to develop new insights that could improve pregnancy outcomes for affected women.
Who could benefit from this research
Good fit: Ideal candidates for this research are pregnant women living with HIV, particularly those experiencing symptoms of bacterial vaginosis.
Not a fit: Patients who are not pregnant or do not have HIV may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better prevention strategies for preterm birth in women with HIV, ultimately improving maternal and infant health.
How similar studies have performed: Previous research has indicated that understanding the vaginal microbiome can significantly impact pregnancy outcomes, suggesting that this approach has potential for success.
Where this research is happening
Baltimore, United States
- Johns Hopkins University — Baltimore, United States (Active)
Researchers
- Principal investigator: Powell, Anna Maya — Johns Hopkins University
- Study coordinator: Powell, Anna Maya
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.