Investigating how Type 1 diabetes affects brain function in children
Official title: Understanding Neurocognition in Youth with Type 1 Diabetes (UNYT1D) Biostatistics Research Center (BRC)
Funded at University of Minnesota · NIH-10975099 · Data updated 2026-11-12
This study is looking at how Type 1 diabetes affects thinking and learning in children, and it wants to find out how things like blood sugar control and stress in caregivers can make a difference, so we can help kids develop better.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Minnesota NIH-funded |
| Lab location | 1 site (Minneapolis, United States) |
| Project start | August 15, 2024 |
| Project end | June 30, 2029 |
| Funding year | 2024 |
| Award (this year) | $1,858,285 |
| NIH project number | 1U01DK140777-01 |
| Project ID | NIH-10975099 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are children aged 0-20 years who have been diagnosed with Type 1 diabetes.
✕Less likely to help
Patients who do not have Type 1 diabetes or are over the age of 20 may not receive any benefit from this research.
What this research studies
This research focuses on understanding the impact of Type 1 diabetes on neurocognitive functions in children. It aims to explore how factors such as glucose control, diabetic ketoacidosis at diagnosis, and caregiver distress influence cognitive development. By conducting a large, diverse, and longitudinal study, the research seeks to identify critical periods for intervention and strategies to prevent neurocognitive complications. The study will involve collecting and analyzing data from a wide range of pediatric patients to ensure comprehensive insights.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for managing Type 1 diabetes in children, potentially enhancing their cognitive development and overall quality of life.
How similar studies have gone: While there is emerging evidence in this area, this research aims to fill gaps left by previous studies, making it a novel and necessary investigation.
Where this research is happening
-
University of Minnesota
Minneapolis, United States Active
Researchers
- Principal investigator: Helgeson, Erika S. — University of Minnesota
- Study coordinator: Helgeson, Erika S.
Related research
Other NIH-funded projects on the same topics.
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Technological and Educational Approaches to Restore Hypoglycemia Awareness in Type 1 Diabetes
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-
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Treating impaired hypoglycemia awareness in type 1 diabetes with targeted education and technology
This study tests two treatment approaches to help adults with type 1 diabetes who often don’t realize their blood sugar is getting too low, using a mix of technology and education in two large groups.
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A UK study tests two different approaches to help adults with type 1 diabetes recognize and respond to low blood sugar by comparing a high-tech insulin system with targeted education.
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How the pancreas environment affects insulin-producing cells in type 1 diabetes
Researchers are studying how the surrounding tissue of the pancreas and its proteins influence insulin-producing cells in people with type 1 diabetes.
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Understanding how hypoglycemia awareness changes in adults with type 1 diabetes and how automated insulin delivery and exercise might help restore it
This study will look at adults with type 1 diabetes to see how their awareness of low blood sugar evolves over time and whether automated insulin delivery and high-intensity exercise can help restore that awareness.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.