Investigating how type 1 diabetes affects brain development in young children
Evaluating Neurocognitive Complications of Type 1 Diabetes (T1D) and Potential Risk and Protective Factors in Pre-Pubertal Children- New York University Clinical Center
This study is looking at how type 1 diabetes affects the brain and thinking skills in young kids, and it’s inviting children with diabetes and those without to help us learn more by doing some fun brain tests and scans over a couple of years.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | New York University School of Medicine NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-10975293 on NIH RePORTER |
What this research studies
This research focuses on understanding the neurocognitive complications associated with type 1 diabetes (T1D) in prepubertal children. It aims to enroll up to 1,000 children, half of whom have been diagnosed with T1D within the last year. Participants will undergo MRI scans and cognitive tests at the start and again at intervals of 18 months to assess changes in brain development and cognitive function. The study will also collect biomedical data to explore how factors like blood sugar control and episodes of diabetic ketoacidosis impact cognitive outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research are prepubertal children aged 0-11 years, particularly those recently diagnosed with type 1 diabetes.
Not a fit: Patients who are older than 11 years or those without a diagnosis of type 1 diabetes may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and management of cognitive issues in children with type 1 diabetes.
How similar studies have performed: Previous research has indicated that cognitive dysfunction is a concern in children with diabetes, suggesting that this investigation builds on established findings.
Where this research is happening
New York, United States
- New York University School of Medicine — New York, United States (Active)
Researchers
- Principal investigator: Gallagher, Mary Patricia — New York University School of Medicine
- Study coordinator: Gallagher, Mary Patricia
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.