Investigating how type 1 diabetes affects brain development in children
Risk and Protective Factors for Neurocognitive Development in Type 1 Diabetes
['FUNDING_U01'] · UNIVERSITY OF CALIFORNIA AT DAVIS · NIH-10974722
This study is looking at how type 1 diabetes affects the thinking and learning skills of children aged 6 to 11, especially those who have just been diagnosed, and it will follow them for over a year and a half to see how different factors, like blood sugar levels, impact their brain health compared to kids without diabetes.
Quick facts
| Phase | ['FUNDING_U01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CALIFORNIA AT DAVIS (nih funded) |
| Locations | 1 site (DAVIS, UNITED STATES) |
| Trial ID | NIH-10974722 on ClinicalTrials.gov |
What this research studies
This research focuses on understanding the impact of type 1 diabetes (T1D) on neurocognitive development in children. It aims to identify risk and protective factors that influence cognitive function over time, particularly in children newly diagnosed with T1D. By comparing children with T1D to those without, the study will explore how factors like diabetic ketoacidosis and blood sugar levels affect brain health. The research will involve a longitudinal cohort of 800 children aged 6 to 11, who will be evaluated and followed for at least 1.5 years to track cognitive changes.
Who could benefit from this research
Good fit: Ideal candidates for this research are children aged 6 to 11 who have recently been diagnosed with type 1 diabetes, particularly those who experienced diabetic ketoacidosis at onset.
Not a fit: Children who do not have type 1 diabetes or are outside the age range of 6 to 11 years may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for managing type 1 diabetes in children, potentially enhancing their cognitive function and overall quality of life.
How similar studies have performed: Previous research has indicated that understanding the cognitive impacts of chronic conditions like diabetes can lead to significant improvements in patient management, suggesting this approach has potential for success.
Where this research is happening
DAVIS, UNITED STATES
- UNIVERSITY OF CALIFORNIA AT DAVIS — DAVIS, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: GHETTI, SIMONA — UNIVERSITY OF CALIFORNIA AT DAVIS
- Study coordinator: GHETTI, SIMONA
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Acquired brain injury