Investigating how Type 1 diabetes affects bone health
Skeletal Effects of Type 1 Diabetes
This study is looking at how Type 1 diabetes affects bone health and increases the risk of fractures, and it's for people with diabetes who want to understand how their condition might impact their bones and what can be done to help keep them strong.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Creighton University NIH-funded |
| Lab location | 1 site (Omaha, United States) |
| Project ID | NIH-10911774 on NIH RePORTER |
What this research studies
This research focuses on understanding the skeletal effects of Type 1 diabetes, particularly how it increases the risk of osteoporotic fractures. The study examines the mechanical properties of bone tissue in diabetic patients, exploring how factors like advanced glycation end-products (AGEs) may weaken bones. By utilizing advanced imaging techniques and analyzing bone density, the research aims to uncover the underlying mechanisms that contribute to fractures in individuals with diabetes. The findings could lead to new treatment strategies to improve bone health in this population.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals aged 21 and older who have been diagnosed with Type 1 diabetes.
Not a fit: Patients without Type 1 diabetes or those under 21 years old may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments that reduce the risk of fractures in patients with Type 1 diabetes.
How similar studies have performed: Previous research has indicated that treatments targeting advanced glycation end-products have shown promise in improving bone health, suggesting that this approach may yield beneficial results.
Where this research is happening
Omaha, United States
- Creighton University — Omaha, United States (Active)
Researchers
- Principal investigator: Akhter, Mohammed Pervez — Creighton University
- Study coordinator: Akhter, Mohammed Pervez
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.