NIH-funded research Fellowship grant

Investigating how trauma affects labor outcomes in Black pregnant individuals

Official title: Prenatal Epigenetics: Trauma and Outcomes of Labor Dysfunction

Funded at Emory University · NIH-10923853 · Data updated 2026-11-12

This study is looking at how trauma affects the labor experience for Black pregnant individuals, aiming to understand how stress might change their bodies in ways that could impact childbirth.

Quick facts

Grant typeFellowship grant
Study typeNIH-funded research
Funding institutionEmory University
NIH-funded
Lab location1 site (Atlanta, United States)
Project startAugust 18, 2023
Project endAugust 17, 2025
Funding year2024
Award (this year)$48,974
NIH project number5F31NR020847-02
Project IDNIH-10923853 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are Black pregnant individuals in their third trimester who have experienced trauma.

Less likely to help

Patients who are not Black or who are not currently pregnant may not receive benefit from this research.

What this research studies

This research examines the impact of trauma on labor outcomes specifically in Black pregnant individuals, who face higher rates of severe maternal morbidity and mortality. By analyzing biological samples and survey data, the study aims to explore the epigenetic changes linked to trauma and how these changes may influence the physiological systems involved in labor. The approach includes an epigenome-wide association study to identify DNA methylation patterns associated with labor dysfunction. The findings could provide insights into the underlying mechanisms that contribute to disparities in maternal health outcomes.

Why it matters

Potential benefit: If successful, this research could lead to improved understanding and interventions for labor complications in Black pregnant individuals, ultimately reducing maternal morbidity and mortality rates.

How similar studies have gone: Other research has shown promising results in understanding the link between trauma and health outcomes, but this specific approach focusing on epigenetics in Black pregnant individuals is relatively novel.

Where this research is happening

  • Emory University
    Atlanta, United States
    Active

Researchers

  • Principal investigator: Britt, Abby — Emory University
  • Study coordinator: Britt, Abby

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
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Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.