Investigating how to regenerate tendon tissue in older adults
In Vivo Model of Human Enthesis Regeneration
This study is looking at ways to help older adults heal better from tendon injuries by using a special material that supports the growth of healthy tendon tissue, which could lead to improved treatments for common tendon problems as we age.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Thomas Jefferson University NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project ID | NIH-10652314 on NIH RePORTER |
What this research studies
This research focuses on understanding and improving the healing process of tendons, particularly in older adults who often experience tendon degeneration. By creating a specialized scaffold that mimics the natural environment of tendon cells, the researchers aim to enhance the regeneration of tendon tissue at the critical junction where tendons attach to bones. The study involves growing human tendon cells on these scaffolds under various conditions to determine the best methods for promoting healthy tissue development. Patients may benefit from advancements in treatments for tendon injuries that are common in aging populations.
Who could benefit from this research
Good fit: Ideal candidates for this research are older adults experiencing tendon-related issues, particularly those with conditions like tendinopathy.
Not a fit: Patients who are younger and do not have tendon degeneration or related injuries may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for tendon injuries, reducing pain and disability in older adults.
How similar studies have performed: Previous research has shown promise in using engineered scaffolds for tissue regeneration, suggesting potential success for this approach.
Where this research is happening
Philadelphia, United States
- Thomas Jefferson University — Philadelphia, United States (Active)
Researchers
- Principal investigator: Mcbeath, Rowena — Thomas Jefferson University
- Study coordinator: Mcbeath, Rowena
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.