Investigating how to predict epilepsy in newborns with seizures
NS-PEACE Neonatal Seizures -Predicting Epilepsy and Assessing Comparative Effectiveness
This study is looking at the best medications to help newborns who have seizures, which can sometimes lead to bigger health issues later on, and it's for families with babies who might be experiencing these seizures.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Weill Medical Coll of Cornell Univ NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-11074027 on NIH RePORTER |
What this research studies
This research focuses on understanding neonatal seizures, which occur in about 1 in 1000 live births and can lead to serious conditions like epilepsy and cerebral palsy. The study aims to determine the most effective medications for treating these seizures and to explore how different treatments may influence the risk of developing further seizure disorders as the child grows. By analyzing data from 780 neonates across 18 medical centers, the researchers will compare the effectiveness of commonly used anti-seizure medications. This research is crucial for improving treatment strategies and outcomes for affected infants.
Who could benefit from this research
Good fit: Ideal candidates for this research are newborns aged 0-28 days who have experienced acute symptomatic seizures.
Not a fit: Patients who do not have neonatal seizures or are older than 28 days may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better treatment options that reduce the risk of developing epilepsy in newborns who experience seizures.
How similar studies have performed: Previous research has shown promising results in the treatment of neonatal seizures, but this specific approach to comparing medication effectiveness is relatively novel.
Where this research is happening
New York, United States
- Weill Medical Coll of Cornell Univ — New York, United States (Active)
Researchers
- Principal investigator: Grinspan, Zachary Michael — Weill Medical Coll of Cornell Univ
- Study coordinator: Grinspan, Zachary Michael
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.