Investigating how to predict and prevent type 2 diabetes in young people.
Understanding, Predicting and Preventing Type 2 Diabetes in Youth, Boston Clinical Center (UPP Study)
['FUNDING_U01'] · JOSLIN DIABETES CENTER · NIH-11053542
This study is looking for kids and teens aged 7-15 who are a bit overweight or have a family history of diabetes to help us understand what might lead to type 2 diabetes, so we can find ways to keep them healthy and prevent the disease.
Quick facts
| Phase | ['FUNDING_U01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | JOSLIN DIABETES CENTER (nih funded) |
| Locations | 1 site (BOSTON, UNITED STATES) |
| Trial ID | NIH-11053542 on ClinicalTrials.gov |
What this research studies
This research focuses on understanding the factors that lead to type 2 diabetes (T2D) in children and adolescents, particularly those who are overweight or have a family history of diabetes. The study will recruit youth aged 7-15 with pre-diabetes and elevated body mass index (BMI) to explore how metabolic and hormonal factors contribute to the progression of T2D. Participants will undergo annual clinical assessments and remote monitoring to gather data on their glucose levels and overall health. The goal is to identify which young individuals are at higher risk of developing T2D and how to intervene effectively.
Who could benefit from this research
Good fit: Ideal candidates for this research are children and adolescents aged 7-15 who are overweight and have pre-diabetes or a family history of diabetes.
Not a fit: Patients who are not in the specified age range or do not have pre-diabetes or related risk factors may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better prediction and prevention strategies for type 2 diabetes in youth, potentially reducing the incidence of this condition.
How similar studies have performed: Previous research has shown promise in understanding diabetes risk factors in youth, but this study aims to provide a more comprehensive approach by combining clinical and remote assessments.
Where this research is happening
BOSTON, UNITED STATES
- JOSLIN DIABETES CENTER — BOSTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: ISGANAITIS, ELVIRA MARIE — JOSLIN DIABETES CENTER
- Study coordinator: ISGANAITIS, ELVIRA MARIE
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: adult onset diabetes, Adult-Onset Diabetes Mellitus