Investigating how to control sulfur biology in the body
The Study of Human Sulfuryl-Transfer Biology
['FUNDING_OTHER'] · ALBERT EINSTEIN COLLEGE OF MEDICINE · NIH-10472518
This study is looking at how a process called sulfonation changes the way some hormones and medications work, and it's trying to find ways to make certain drugs better at treating conditions like Parkinson's disease and thyroid issues, so patients can have more effective treatments with fewer side effects.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | ALBERT EINSTEIN COLLEGE OF MEDICINE (nih funded) |
| Locations | 1 site (BRONX, UNITED STATES) |
| Trial ID | NIH-10472518 on ClinicalTrials.gov |
What this research studies
This research focuses on understanding how sulfonation affects various signaling molecules in the body, including hormones and drugs. By developing methods to prevent the sulfonation of specific compounds, the researchers aim to enhance the effectiveness of certain medications without interfering with their normal functions. The study will involve creating and testing modified versions of existing drugs to improve their efficacy in treating conditions like Parkinson's disease and regulating thyroid hormones. Patients may benefit from new treatment options that are more effective and have fewer side effects.
Who could benefit from this research
Good fit: Ideal candidates include individuals with Parkinson's disease or those requiring hormonal regulation.
Not a fit: Patients who do not have conditions related to sulfonation or hormonal imbalances may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for conditions like Parkinson's disease and improved hormonal regulation.
How similar studies have performed: While the specific approach of controlling sulfonation is relatively novel, similar strategies in drug modification have shown promise in other research.
Where this research is happening
BRONX, UNITED STATES
- ALBERT EINSTEIN COLLEGE OF MEDICINE — BRONX, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: LEYH, THOMAS S. — ALBERT EINSTEIN COLLEGE OF MEDICINE
- Study coordinator: LEYH, THOMAS S.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.