Investigating how tissue structure affects jaw joint function and differences by sex and race
Tissue structure and mechanical function relationships of the human temporomandibular lateral capsule-ligament: Investigation of sexual and racial dimorphisms
['FUNDING_OTHER'] · UNIVERSITY OF ROCHESTER · NIH-11261492
This study is looking at how the structure of a part of your jaw affects its function, especially to understand why more women and African Americans have jaw pain issues, so we can find better ways to help those who suffer from it.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF ROCHESTER (nih funded) |
| Locations | 1 site (ROCHESTER, UNITED STATES) |
| Trial ID | NIH-11261492 on ClinicalTrials.gov |
What this research studies
This research explores the relationships between the structure of the temporomandibular lateral capsule-ligament and its mechanical function, particularly focusing on how these relationships differ between sexes and racial groups. By examining the properties of the temporomandibular joint, the study aims to uncover the underlying reasons for the higher incidence of temporomandibular disorders (TMDs) in females and African Americans. The approach involves analyzing tissue samples and mechanical properties to identify potential risk factors for TMD development. The ultimate goal is to enhance individualized risk assessments for TMDs, which could lead to more tailored treatment options for patients.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals experiencing temporomandibular disorders, especially those who are female or identify as African American.
Not a fit: Patients who do not have temporomandibular disorders or those outside the specified demographic groups may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and management of temporomandibular disorders, particularly for women and African American patients.
How similar studies have performed: While there has been some research on sex differences in TMDs, this study's specific focus on racial dimorphisms is relatively novel and has not been extensively explored.
Where this research is happening
ROCHESTER, UNITED STATES
- UNIVERSITY OF ROCHESTER — ROCHESTER, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: HILL, CHERICE NATASHA — UNIVERSITY OF ROCHESTER
- Study coordinator: HILL, CHERICE NATASHA
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.