Investigating how tiny hair-like structures in the fallopian tube affect fertility
Official title: In vivo investigation of cilia function in the fallopian tube
Funded at Baylor College of Medicine · NIH-10991728 · Data updated 2026-11-12
This study is looking at tiny hair-like structures in the fallopian tubes to see how they help with female fertility, hoping to find new ways to help women who are having trouble getting pregnant.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Baylor College of Medicine NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project start | December 1, 2023 |
| Project end | November 30, 2028 |
| Funding year | 2025 |
| Award (this year) | $573,562 |
| NIH project number | 5R01HD112102-02 |
| Project ID | NIH-10991728 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are women experiencing fertility issues or conditions related to ciliary dysfunction.
✕Less likely to help
Patients who are not experiencing fertility problems or do not have conditions related to ciliary function may not benefit from this research.
What this research studies
This research focuses on understanding the function of cilia, which are small hair-like structures in the fallopian tube, and their role in female fertility. Using advanced imaging technology, the study will observe these cilia in live mice to see how they contribute to reproductive processes and how their dysfunction may lead to infertility or ectopic pregnancies. By examining the dynamics of cilia in a natural environment, the research aims to provide insights that could improve treatments for women facing fertility challenges.
Why it matters
Potential benefit: If successful, this research could lead to new treatments for infertility and better understanding of reproductive health in women.
How similar studies have gone: While the investigation of cilia in reproductive health is a relatively novel approach, previous studies have shown that understanding ciliary function can lead to significant advancements in treating related disorders.
Where this research is happening
-
Baylor College of Medicine
Houston, United States Active
Researchers
- Principal investigator: Larina, Irina — Baylor College of Medicine
- Study coordinator: Larina, Irina
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.