Investigating how the shape of tissues is formed and maintained in fruit flies.
Physical aspects of Drosophila Gastrulation
This study looks at how the shapes of tissues form in fruit flies, which can help us understand how our own tissues develop and function, potentially leading to better treatments for related health issues.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Ut Southwestern Medical Center NIH-funded |
| Lab location | 1 site (Dallas, United States) |
| Project ID | NIH-11123437 on NIH RePORTER |
What this research studies
This research explores the physical mechanisms that determine the shape of tissues in animals, focusing on the process of morphogenesis in fruit flies (Drosophila). By combining biophysical measurements and modeling techniques, the study aims to quantify the mechanical properties of different tissue regions and understand the active forces driving tissue deformation. This approach will provide insights into how specific shapes are specified and maintained during development, which is crucial for proper organ function. Patients may benefit from the findings as they could lead to a better understanding of tissue development and related disorders.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research would include individuals with developmental disorders or conditions related to tissue formation.
Not a fit: Patients with conditions unrelated to tissue morphology or development may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could enhance our understanding of tissue development, potentially leading to improved treatments for developmental disorders.
How similar studies have performed: Other research has shown success in understanding tissue mechanics and morphogenesis, indicating that this approach has a foundation in established scientific inquiry.
Where this research is happening
Dallas, United States
- Ut Southwestern Medical Center — Dallas, United States (Active)
Researchers
- Principal investigator: Doubrovinski, Konstantin — Ut Southwestern Medical Center
- Study coordinator: Doubrovinski, Konstantin
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.