Investigating how the shape of nanoparticles affects their interaction with cells.
Continuous Probing of Nanoconstruct-Cell Interactions at Biologically Relevant Time Scales
['FUNDING_R01'] · NORTHWESTERN UNIVERSITY · NIH-10914140
This study is looking at how the shape of tiny particles used in medicine affects their ability to find and connect with cells, especially when they're surrounded by proteins in the body, and it aims to find better ways to deliver drugs by using light to control these particles.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | NORTHWESTERN UNIVERSITY (nih funded) |
| Locations | 1 site (Chicago, UNITED STATES) |
| Trial ID | NIH-10914140 on ClinicalTrials.gov |
What this research studies
This research focuses on understanding how the shape of nanoparticle-based constructs influences their ability to target and interact with cells. By using advanced imaging techniques, the study examines how these nanoparticles maintain their targeting capabilities even when surrounded by proteins in the biological environment. The researchers aim to uncover the mechanisms behind these interactions and explore ways to enhance the effectiveness of drug delivery systems using light to control the behavior of these nanoparticles in real-time.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients who may benefit from advanced drug delivery methods, particularly those with conditions requiring targeted therapies.
Not a fit: Patients who do not require targeted drug delivery or those with conditions that do not involve cellular interactions with nanoparticles may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective drug delivery systems that improve treatment outcomes for patients.
How similar studies have performed: Previous research has shown promising results in using nanoparticle constructs for targeted drug delivery, indicating that this approach has potential for success.
Where this research is happening
Chicago, UNITED STATES
- NORTHWESTERN UNIVERSITY — Chicago, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: ODOM, TERI WANG — NORTHWESTERN UNIVERSITY
- Study coordinator: ODOM, TERI WANG
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.