Investigating how the novel coronavirus affects the brain
How the Novel Coronavirus Attacks the Brain
This study is looking at how COVID-19 affects the brain, especially for people who are still having problems like trouble thinking or losing their sense of smell, to help find better ways to treat these issues.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | New York State Psychiatric Institute Dba Research Foundation for Mental Hygiene, INC NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-10450852 on NIH RePORTER |
What this research studies
This research explores the neurological effects of SARS-CoV-2 infection, focusing on symptoms such as loss of smell, confusion, and cognitive difficulties. By examining brain tissue from deceased COVID-19 patients, the study aims to understand how the virus invades brain cells and the resulting damage. The research will analyze the interplay between inflammation, blood vessel damage, and neurological symptoms to identify potential targets for treatment. Patients with long-term neurological issues post-COVID-19 may find insights that could lead to better management of their conditions.
Who could benefit from this research
Good fit: Ideal candidates include individuals who have experienced neurological symptoms following COVID-19 infection, such as loss of smell or cognitive difficulties.
Not a fit: Patients who have not been infected with SARS-CoV-2 or do not exhibit neurological symptoms may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and treatment options for neurological symptoms associated with COVID-19.
How similar studies have performed: While the specific mechanisms of SARS-CoV-2's impact on the brain are still being explored, similar research has shown promising results in understanding viral effects on neurological health.
Where this research is happening
New York, United States
- New York State Psychiatric Institute Dba Research Foundation for Mental Hygiene, INC — New York, United States (Active)
Researchers
- Principal investigator: Boldrini, Maura — New York State Psychiatric Institute Dba Research Foundation for Mental Hygiene, INC
- Study coordinator: Boldrini, Maura
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.