Investigating how the MIND diet affects brain health and Alzheimer's disease through metabolic signatures.
Official title: Metabolic signatures of the MIND diet to objectively investigate with all cause and Alzheimer’s Disease dementia and PET imaging Biomarkers of Alzheimer's Disease
Funded at University of Texas Hlth Science Center · NIH-10890937 · Data updated 2026-11-12
This study is looking at how the MIND diet, which mixes the Mediterranean and DASH diets, might help keep your brain healthy and reduce the risk of Alzheimer's disease, and it's for people who want to learn more about how what they eat can affect their brain health.
Quick facts
| Grant type | R03 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Texas Hlth Science Center NIH-funded |
| Lab location | 1 site (San Antonio, United States) |
| Project start | June 1, 2024 |
| Project end | May 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $334,297 |
| NIH project number | 1R03AG087437-01 |
| Project ID | NIH-10890937 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals who are at risk for Alzheimer's disease or those interested in dietary interventions for brain health.
✕Less likely to help
Patients who are not at risk for Alzheimer's disease or those who do not follow the MIND diet may not benefit from this research.
What this research studies
This research explores the impact of the MIND diet, which combines elements of the Mediterranean and DASH diets, on brain health and Alzheimer's disease. By analyzing metabolic signatures and using advanced PET imaging techniques, the study aims to identify how dietary patterns influence neurodegenerative outcomes. Participants will be drawn from the Framingham Heart Study, and their metabolic profiles will be assessed to understand the relationship between diet and brain health. This personalized approach seeks to uncover individual responses to the MIND diet and its potential protective effects against dementia.
Why it matters
Potential benefit: If successful, this research could lead to dietary recommendations that significantly reduce the risk of Alzheimer's disease and improve brain health.
How similar studies have gone: Previous research has shown promising results in dietary interventions for brain health, suggesting that this approach may yield valuable insights.
Where this research is happening
-
University of Texas Hlth Science Center
San Antonio, United States Active
Researchers
- Principal investigator: Melo Van Lent, Debora — University of Texas Hlth Science Center
- Study coordinator: Melo Van Lent, Debora
Related research
Other NIH-funded projects on the same topics.
-
Global picture of dementia risk and memory loss across the world
A large international effort gathers data from many studies to understand how dementia and memory problems develop around the world, using shared information to reveal patterns and risk factors.
-
Automated language analysis for Alzheimer’s disease and frontotemporal dementia in Latino and English speakers
A low-cost, automated speech and language analysis tool is being developed to help identify Alzheimer’s disease or frontotemporal dementia in Latino and English-speaking people.
-
Automated language analysis for Alzheimer’s and frontotemporal dementia across Latino and English-speaking groups
A low-cost, automated language study aims to help diagnose and understand Alzheimer’s and FTD in diverse Spanish- and English-speaking communities.
-
Automated language analysis to help diagnose Alzheimer’s and frontotemporal dementia in Latino and English speakers
A low-cost, computer-based method analyzes speech and language to help identify Alzheimer’s disease or frontotemporal dementia in Latino and English-speaking people.
-
Automated language analysis for Alzheimer's and frontotemporal dementia in Latino and English-speaking communities
A low-cost, computer-based language analysis method is being developed to help identify Alzheimer’s disease and frontotemporal dementia in Latino and English-speaking people.
-
Automated language analysis to detect Alzheimer’s and frontotemporal dementia in Latino and English-speaking adults
A low-cost, computer-based language and speech analysis tool will help identify Alzheimer’s disease and frontotemporal dementia in Latino and English-speaking adults.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.