Investigating how the lungs respond to a new bronchoscopic treatment for emphysema
Imaging the functional response of the lung to bronchoscopic lung volume reduction
This study is looking at how a special procedure using tiny valves can help people with emphysema breathe better, and it aims to find out who might benefit the most from this treatment by tracking their lung function and quality of life over time.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pennsylvania NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project ID | NIH-10898053 on NIH RePORTER |
What this research studies
This research focuses on understanding the functional response of the lungs to a bronchoscopic procedure known as lung volume reduction using Zephyr Endobronchial Valves. The approach involves inserting valves via a catheter to occlude parts of the lung affected by emphysema, which can help improve breathing mechanics and lung function. By monitoring changes in lung function and quality of life, the study aims to identify which patients benefit most from this treatment. The research will utilize advanced imaging techniques to assess the effectiveness of this procedure over time.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with advanced emphysema who may benefit from bronchoscopic lung volume reduction techniques.
Not a fit: Patients with mild emphysema or those who are not suitable candidates for bronchoscopic procedures may not receive benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment options for patients with advanced emphysema, enhancing their quality of life and lung function.
How similar studies have performed: Previous studies have shown promising results with similar bronchoscopic techniques, indicating potential for significant improvements in lung function and quality of life.
Where this research is happening
Philadelphia, United States
- University of Pennsylvania — Philadelphia, United States (Active)
Researchers
- Principal investigator: Rizi, Rahim R — University of Pennsylvania
- Study coordinator: Rizi, Rahim R
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.