Investigating how the immune system responds to rhinovirus in people with allergic asthma
Official title: Exploring innate immune responses to rhinovirus in allergic asthma
Funded at University of Virginia · NIH-11140038 · Data updated 2026-11-12
This study is looking at how the immune system reacts to common cold viruses in people with allergic asthma to find out why some folks have worse asthma attacks, with the hope of discovering better ways to treat it.
Quick facts
| Grant type | R03 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Virginia NIH-funded |
| Lab location | 1 site (Charlottesville, United States) |
| Project start | May 28, 2025 |
| Project end | April 30, 2027 |
| Funding year | 2025 |
| Award (this year) | $80,750 |
| NIH project number | 1R03AI185854-01A1 |
| Project ID | NIH-11140038 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with allergic asthma, including both children and adults, who may experience exacerbations due to rhinovirus infections.
✕Less likely to help
Patients without asthma or those whose asthma is not related to allergic responses may not benefit from this research.
What this research studies
This research focuses on understanding the immune responses triggered by rhinovirus infections in individuals with allergic asthma. By examining how the immune system reacts during the early stages of infection, the study aims to uncover why some patients experience severe asthma exacerbations. The researchers will utilize an experimental model to monitor patients closely and analyze immune responses before symptoms worsen. This approach could provide insights into the mechanisms behind asthma attacks and help develop better treatments.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for preventing asthma exacerbations triggered by viral infections.
How similar studies have gone: Previous research has shown promising results in understanding immune responses in asthma, but this specific approach using an experimental rhinovirus infection model is relatively novel.
Where this research is happening
-
University of Virginia
Charlottesville, United States Active
Researchers
- Principal investigator: Borish, Larry C — University of Virginia
- Study coordinator: Borish, Larry C
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.