Investigating how the immune system responds to rhinovirus in people with allergic asthma
Exploring innate immune responses to rhinovirus in allergic asthma
['FUNDING_R03'] · UNIVERSITY OF VIRGINIA · NIH-11140038
This study is looking at how the immune system reacts to common cold viruses in people with allergic asthma to find out why some folks have worse asthma attacks, with the hope of discovering better ways to treat it.
Quick facts
| Phase | ['FUNDING_R03'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF VIRGINIA (nih funded) |
| Locations | 1 site (CHARLOTTESVILLE, UNITED STATES) |
| Trial ID | NIH-11140038 on ClinicalTrials.gov |
What this research studies
This research focuses on understanding the immune responses triggered by rhinovirus infections in individuals with allergic asthma. By examining how the immune system reacts during the early stages of infection, the study aims to uncover why some patients experience severe asthma exacerbations. The researchers will utilize an experimental model to monitor patients closely and analyze immune responses before symptoms worsen. This approach could provide insights into the mechanisms behind asthma attacks and help develop better treatments.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with allergic asthma, including both children and adults, who may experience exacerbations due to rhinovirus infections.
Not a fit: Patients without asthma or those whose asthma is not related to allergic responses may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for preventing asthma exacerbations triggered by viral infections.
How similar studies have performed: Previous research has shown promising results in understanding immune responses in asthma, but this specific approach using an experimental rhinovirus infection model is relatively novel.
Where this research is happening
CHARLOTTESVILLE, UNITED STATES
- UNIVERSITY OF VIRGINIA — CHARLOTTESVILLE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: BORISH, LARRY C — UNIVERSITY OF VIRGINIA
- Study coordinator: BORISH, LARRY C
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: acute infection