Investigating how the immune system affects lung blood vessel diseases.
Complement Mediated Remodeling in Pulmonary Vascular Disease
This study is looking at pulmonary arterial hypertension (PAH) to learn more about how it affects different people in different ways, so we can create better, personalized treatments, and we’d love for patients to help by sharing their experiences and samples.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Colorado Denver NIH-funded |
| Lab location | 1 site (Aurora, UNITED STATES) |
| Project ID | NIH-10911054 on NIH RePORTER |
What this research studies
This research focuses on pulmonary arterial hypertension (PAH), a serious condition affecting the blood vessels in the lungs. It aims to understand the various factors that contribute to the disease's complexity, including how different patients may experience different symptoms and responses to treatment. By studying the underlying biological processes and patient-specific characteristics, the research seeks to develop more personalized and effective therapies for PAH. Patients may be involved in providing samples or data to help identify these unique disease mechanisms.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with pulmonary arterial hypertension, regardless of age or sex.
Not a fit: Patients with pulmonary arterial hypertension who are not responsive to current therapies or have other unrelated health conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more targeted and effective treatments for patients with pulmonary arterial hypertension.
How similar studies have performed: Previous research has shown promise in understanding the heterogeneity of pulmonary arterial hypertension, indicating that this approach could lead to significant advancements in treatment.
Where this research is happening
Aurora, UNITED STATES
- University of Colorado Denver — Aurora, United States (Active)
Researchers
- Principal investigator: Stenmark, Kurt R. — University of Colorado Denver
- Study coordinator: Stenmark, Kurt R.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.