Investigating how the epithelial extracellular matrix affects drug delivery and absorption.
Official title: The epithelial matrisome and drug transport kinetics
Funded at Oregon State University · NIH-11126550 · Data updated 2026-11-12
This study is looking at how the layer of proteins in our body helps medicines get absorbed better, so we can find ways to make treatments work more effectively for different health issues.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Oregon State University NIH-funded |
| Lab location | 1 site (Corvallis, United States) |
| Project start | August 1, 2023 |
| Project end | May 31, 2028 |
| Funding year | 2025 |
| Award (this year) | $351,252 |
| NIH project number | 5R35GM151254-03 |
| Project ID | NIH-11126550 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals who are undergoing treatment that requires effective drug absorption and delivery.
✕Less likely to help
Patients with conditions that do not involve epithelial barriers or drug absorption issues may not benefit from this research.
What this research studies
This research focuses on understanding the epithelial extracellular matrix (ECM) and its role in drug transport and absorption. By using advanced computational tools and three-dimensional models, the research aims to explore how external factors influence the ECM and how these changes can impact the effectiveness of drug delivery. The study will analyze the complex network of proteins within the ECM to identify ways to enhance drug bioavailability, which could lead to more effective treatments for various conditions.
Why it matters
Potential benefit: If successful, this research could lead to improved drug delivery methods, making treatments more effective for patients.
How similar studies have gone: Other research has shown promise in using 3D modeling and ECM analysis to improve drug delivery, indicating that this approach has potential for success.
Where this research is happening
-
Oregon State University
Corvallis, United States Active
Researchers
- Principal investigator: Fogg, Kaitlin C — Oregon State University
- Study coordinator: Fogg, Kaitlin C
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.