Investigating how the epithelial extracellular matrix affects drug delivery and absorption.
The epithelial matrisome and drug transport kinetics
['FUNDING_OTHER'] · OREGON STATE UNIVERSITY · NIH-11126550
This study is looking at how the layer of proteins in our body helps medicines get absorbed better, so we can find ways to make treatments work more effectively for different health issues.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | OREGON STATE UNIVERSITY (nih funded) |
| Locations | 1 site (CORVALLIS, UNITED STATES) |
| Trial ID | NIH-11126550 on ClinicalTrials.gov |
What this research studies
This research focuses on understanding the epithelial extracellular matrix (ECM) and its role in drug transport and absorption. By using advanced computational tools and three-dimensional models, the research aims to explore how external factors influence the ECM and how these changes can impact the effectiveness of drug delivery. The study will analyze the complex network of proteins within the ECM to identify ways to enhance drug bioavailability, which could lead to more effective treatments for various conditions.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals who are undergoing treatment that requires effective drug absorption and delivery.
Not a fit: Patients with conditions that do not involve epithelial barriers or drug absorption issues may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved drug delivery methods, making treatments more effective for patients.
How similar studies have performed: Other research has shown promise in using 3D modeling and ECM analysis to improve drug delivery, indicating that this approach has potential for success.
Where this research is happening
CORVALLIS, UNITED STATES
- OREGON STATE UNIVERSITY — CORVALLIS, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: FOGG, KAITLIN C — OREGON STATE UNIVERSITY
- Study coordinator: FOGG, KAITLIN C
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.