Investigating how the environment around tumors affects breast cancer after pregnancy
The Tumor Microenvironment and Lymphatic Remodeling in Postpartum Breast Cancer
This study is looking at how pregnancy might change the way breast cancer behaves, especially for new moms, to find ways to lower the risk and improve treatment for those who develop postpartum breast cancer.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Columbia University Health Sciences NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-10877903 on NIH RePORTER |
What this research studies
This research focuses on understanding postpartum breast cancer (PPBC), which can be more aggressive and deadly compared to other types of breast cancer. The study examines how changes in the tumor microenvironment and lymphatic system during and after pregnancy may contribute to the increased risk of PPBC. By analyzing the immune cells and other factors in the tumor environment, the research aims to identify potential strategies to reduce the risk and improve outcomes for women diagnosed with PPBC. The findings could lead to better risk stratification and treatment options tailored for young women.
Who could benefit from this research
Good fit: Ideal candidates for this research are women who have recently given birth and are at risk for postpartum breast cancer.
Not a fit: Patients who are not postpartum or those who have not been diagnosed with breast cancer may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide new insights and strategies to reduce the risk of aggressive breast cancer in postpartum women.
How similar studies have performed: While there is limited research specifically on postpartum breast cancer, studies on tumor microenvironments and immune responses have shown promise in other cancer types.
Where this research is happening
New York, United States
- Columbia University Health Sciences — New York, United States (Active)
Researchers
- Principal investigator: Mcdonald, Jasmine Alise — Columbia University Health Sciences
- Study coordinator: Mcdonald, Jasmine Alise
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.