Investigating how the age of tissue samples affects the accuracy of transcriptomics in pancreatic cancer.
Effects of Tissue Block Age on Reliability and Accuracy of In situ Transcriptomics Across Organ Sites using Xenium Technology
This study is looking at how the age of tissue samples affects the accuracy of tests that analyze genes in different organs, especially for pancreatic cancer, to help us understand early signs of the disease and improve future detection and treatment for patients.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Tx Md Anderson Can Ctr NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project ID | NIH-11099426 on NIH RePORTER |
What this research studies
This research focuses on understanding the impact of tissue block age on the reliability and accuracy of transcriptomic analyses across different organ sites, particularly in the context of pancreatic cancer. By utilizing advanced Xenium technology, the study aims to explore how the molecular characteristics of pancreatic precursor lesions can be better understood, potentially leading to earlier detection of pancreatic ductal adenocarcinoma (PDAC). Patients may benefit from insights gained about the early stages of cancer development, which could inform future diagnostic and therapeutic strategies.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals at risk for pancreatic cancer, particularly those with known precursor lesions or family history of the disease.
Not a fit: Patients with advanced pancreatic cancer or those without any risk factors for pancreatic cancer may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved early detection methods for pancreatic cancer, enhancing patient outcomes.
How similar studies have performed: Previous research has shown promise in utilizing transcriptomics for cancer detection, suggesting that this approach may yield valuable insights.
Where this research is happening
Houston, United States
- University of Tx Md Anderson Can Ctr — Houston, United States (Active)
Researchers
- Principal investigator: Maitra, Anirban — University of Tx Md Anderson Can Ctr
- Study coordinator: Maitra, Anirban
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.