Investigating how THC affects eye movement and thinking skills based on cannabis use history
Examining the Role of Tolerance on Dose-dependent Effects of Acute THC on Oculomotor and Cognitive Performance
This study is looking at how different amounts of THC from cannabis affect thinking and eye movement skills in people who use cannabis in different ways, to help us understand how it might impact things like driving or working.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project ID | NIH-10665800 on NIH RePORTER |
What this research studies
This research examines how different doses of THC, the active component in cannabis, impact cognitive and oculomotor performance, particularly in individuals with varying levels of cannabis use. By utilizing advanced oculomotor assessments and machine learning techniques, the study aims to identify how THC impairment differs among users. Participants will undergo tests to measure their cognitive abilities and eye movements after THC administration, helping to understand the relationship between cannabis use and performance impairment. The findings could lead to improved methods for detecting THC impairment in real-world settings such as driving and workplaces.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who use cannabis, particularly those with varying levels of tolerance to THC.
Not a fit: Patients who do not use cannabis or have never been exposed to THC may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better detection methods for THC impairment, enhancing public safety and workplace health.
How similar studies have performed: Previous research has shown promising results in using oculomotor assessments to detect impairment from THC, indicating that this approach has potential for success.
Where this research is happening
Baltimore, United States
- Johns Hopkins University — Baltimore, United States (Active)
Researchers
- Principal investigator: Lee, Dustin Clark — Johns Hopkins University
- Study coordinator: Lee, Dustin Clark
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.