Investigating how testosterone may help reduce pain in women using opioids
Exploring the Role of Testosterone as a Novel Anti-Nociceptive Agent in Women with Chronic Pain and Opioid Use
['FUNDING_R21'] · BRIGHAM AND WOMEN'S HOSPITAL · NIH-10413965
This study is looking at how testosterone might help relieve chronic pain in women who are using opioid medications, especially since lower testosterone levels could make pain feel worse and lead to needing more painkillers.
Quick facts
| Phase | ['FUNDING_R21'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | BRIGHAM AND WOMEN'S HOSPITAL (nih funded) |
| Locations | 1 site (BOSTON, UNITED STATES) |
| Trial ID | NIH-10413965 on ClinicalTrials.gov |
What this research studies
This research explores the potential of testosterone as a pain-relieving agent specifically for women suffering from chronic pain and using opioid medications. It examines how lower testosterone levels in women, especially those on opioids, may contribute to increased pain sensitivity and the need for higher doses of painkillers. By understanding the relationship between testosterone and pain, the study aims to identify new treatment strategies that could improve pain management for these patients. The approach includes assessing testosterone levels and their effects on pain perception and opioid use.
Who could benefit from this research
Good fit: Ideal candidates for this research are women experiencing chronic pain who are currently using opioid medications.
Not a fit: Patients who are not using opioids or do not have chronic pain may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatment options that enhance pain relief for women with chronic pain, potentially reducing their reliance on opioids.
How similar studies have performed: Previous research has indicated that testosterone may have pain-relieving properties, suggesting that this approach could yield significant insights and advancements in pain management.
Where this research is happening
BOSTON, UNITED STATES
- BRIGHAM AND WOMEN'S HOSPITAL — BOSTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: BASARIA, SHEHZAD — BRIGHAM AND WOMEN'S HOSPITAL
- Study coordinator: BASARIA, SHEHZAD
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.