Investigating how taurine may protect the brain in Alzheimer's disease
Protective roles of taurine in Alzheimer's disease brain
This study is looking at how a supplement called taurine might help protect the brain in mice with Alzheimer's disease, to see if it can slow down the symptoms and improve brain health for people with the condition.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Massachusetts General Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-10875703 on NIH RePORTER |
What this research studies
This research explores the protective effects of taurine, a dietary supplement, in a mouse model of Alzheimer's disease. The study will measure how taurine is taken up by the brain and its synthesis rates using advanced imaging techniques. Researchers will assess the extent to which taurine supplementation can slow the progression of Alzheimer's symptoms through various tests and post-mortem analysis of brain tissue. The findings aim to enhance understanding of taurine's role in brain health and its potential as a therapeutic option for Alzheimer's patients.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals at risk for or diagnosed with Alzheimer's disease.
Not a fit: Patients with other forms of dementia unrelated to Alzheimer's may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new dietary interventions that help slow the progression of Alzheimer's disease.
How similar studies have performed: Previous research has indicated potential benefits of taurine in neuroprotection, but this specific approach in Alzheimer's is novel.
Where this research is happening
Boston, United States
- Massachusetts General Hospital — Boston, United States (Active)
Researchers
- Principal investigator: Jenkins, Bruce G — Massachusetts General Hospital
- Study coordinator: Jenkins, Bruce G
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.