Investigating how synthetic opioids affect HIV
Omics analysis of HIV during synthetic opioid exposure
This study is looking at how using synthetic opioids, like fentanyl, might affect people living with HIV, especially how these drugs could change the way HIV behaves in the body, with the goal of finding better treatment options for those dealing with both HIV and opioid use.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Cincinnati NIH-funded |
| Lab location | 1 site (Cincinnati, United States) |
| Project ID | NIH-10548205 on NIH RePORTER |
What this research studies
This research explores the relationship between synthetic opioid use and HIV infection. It focuses on understanding how opioids like fentanyl influence HIV latency and reactivation in the body. By conducting in vivo studies, the research aims to evaluate various biological markers related to HIV and the effects of opioids on these markers. This could lead to improved treatment strategies for individuals affected by both HIV and opioid use disorder.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with HIV who also have a history of synthetic opioid use.
Not a fit: Patients who do not have HIV or a history of synthetic opioid use may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better treatment options for patients with HIV who are also struggling with opioid use disorder.
How similar studies have performed: While the specific interactions between synthetic opioids and HIV are not extensively studied, related research has shown that understanding drug interactions can lead to significant advancements in treatment.
Where this research is happening
Cincinnati, United States
- University of Cincinnati — Cincinnati, United States (Active)
Researchers
- Principal investigator: Blackard, Jason T — University of Cincinnati
- Study coordinator: Blackard, Jason T
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.