Investigating how synthetic coolants in vaping products affect addiction behaviors
Determining the impact of synthetic coolants on abuse liability and initiation-related behaviors
This study is looking at how new synthetic coolants in vaping products might affect how people get addicted to nicotine, especially as menthol flavors are being banned, and it’s designed to help guide public health decisions.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Marshall University NIH-funded |
| Lab location | 1 site (Huntington, UNITED STATES) |
| Project ID | NIH-11084577 on NIH RePORTER |
What this research studies
This research focuses on understanding the effects of synthetic coolants, which are increasingly used in vaping products, on addiction-related behaviors associated with nicotine. As menthol flavors are being banned, these synthetic alternatives may mimic menthol's impact on addiction. The study will employ a novel vapor self-administration assay to link vaping behaviors to biological markers of nicotine abuse. By identifying how these coolants influence addiction, the research aims to inform public health policies and regulatory decisions.
Who could benefit from this research
Good fit: Ideal candidates for this research include adolescents and young adults who use or are at risk of using vaping products containing synthetic coolants.
Not a fit: Patients who do not use vaping products or have no interest in nicotine-related behaviors may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better regulations on vaping products, potentially reducing addiction rates among users.
How similar studies have performed: While the specific focus on synthetic coolants is novel, previous research has shown that flavoring agents can significantly impact addiction behaviors in nicotine products.
Where this research is happening
Huntington, UNITED STATES
- Marshall University — Huntington, United States (Active)
Researchers
- Principal investigator: Henderson, Brandon Jarrod — Marshall University
- Study coordinator: Henderson, Brandon Jarrod
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.