Investigating how sugar waste products affect prostate cancer in African American men
Official title: Cause and Effect Relationships Between Glycation and the Ancestry Specific Tumor Stroma
Funded at Virginia Commonwealth University · NIH-11001456 · Data updated 2026-11-12
This study is looking at how certain waste products from sugar in our bodies might affect prostate cancer in African American men, with the hope of finding ways to improve diet and treatment options for better health.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Virginia Commonwealth University NIH-funded |
| Lab location | 1 site (Richmond, United States) |
| Project start | January 1, 2023 |
| Project end | December 31, 2027 |
| Funding year | 2025 |
| Award (this year) | $423,458 |
| NIH project number | 5R01CA259415-03 |
| Project ID | NIH-11001456 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are African American men who are at risk for or diagnosed with prostate cancer.
✕Less likely to help
Patients who are not of African descent or those without prostate cancer may not receive direct benefits from this research.
What this research studies
This research explores the relationship between advanced glycation end products (AGEs) and prostate cancer, particularly in African American men. It examines how the accumulation of AGEs, which are waste products from sugar metabolism, can accelerate tumor growth and influence the tumor environment. By analyzing dietary impacts and the biological mechanisms involved, the study aims to establish a direct cause-and-effect link between AGEs and cancer progression. Patients may benefit from insights that could lead to improved dietary recommendations and treatment strategies.
Why it matters
Potential benefit: If successful, this research could lead to targeted dietary interventions that may slow down or prevent the progression of prostate cancer in at-risk populations.
How similar studies have gone: Previous research has indicated that dietary factors and metabolic waste products can influence cancer progression, suggesting that this approach may yield valuable insights.
Where this research is happening
-
Virginia Commonwealth University
Richmond, United States Active
Researchers
- Principal investigator: Turner, David Paul — Virginia Commonwealth University
- Study coordinator: Turner, David Paul
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.