Investigating how stress affects the growth of uterine fibroids in Black women
Official title: Multiple Stress Pathways and Positive Resources in UF Incidence and Growth
Funded at University of Michigan at Ann Arbor · NIH-11080991 · Data updated 2026-11-12
This study is looking at how different life stresses might affect the development and growth of uterine fibroids in Black women, and it involves over 1,600 women from Detroit who will have check-ups to see how these stresses impact their health.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Michigan at Ann Arbor NIH-funded |
| Lab location | 1 site (Ann Arbor, United States) |
| Project start | May 1, 2024 |
| Project end | January 31, 2029 |
| Funding year | 2025 |
| Award (this year) | $357,886 |
| NIH project number | 5P50HD115356-02 |
| Project ID | NIH-11080991 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are Black women aged 23-34 who have never been diagnosed with uterine fibroids.
✕Less likely to help
Patients who are not Black or those who have already been diagnosed with uterine fibroids may not benefit from this research.
What this research studies
This research focuses on understanding the impact of various life stressors on the incidence and growth of uterine fibroids, particularly in Black women who are disproportionately affected by this condition. By utilizing the Stress Process Model, the study will analyze data collected from over 1,600 Black women in the Detroit area, examining how different stress pathways contribute to the development of fibroids. Participants will undergo assessments, including transvaginal ultrasounds, to track fibroid growth and related health outcomes over time.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and management of uterine fibroids, particularly for Black women, potentially reducing health disparities.
How similar studies have gone: Previous research has indicated that stress can influence various health conditions, but this specific approach focusing on uterine fibroids in Black women is relatively novel.
Where this research is happening
-
University of Michigan at Ann Arbor
Ann Arbor, United States Active
Researchers
- Principal investigator: Wegienka, Ganesa Rebecca — University of Michigan at Ann Arbor
- Study coordinator: Wegienka, Ganesa Rebecca
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.