NIH-funded research R01 grant

Investigating how staying awake at night affects suicide risk

Official title: The Mind After Midnight: Mechanistic Examination of Nocturnal Wakefulness as aSuicide Risk Factor

Funded at University of Arizona · NIH-11048053 · Data updated 2026-11-12

This study is looking at how staying awake at night might affect your feelings and thoughts, especially if you're at risk for suicide, and it aims to find ways to help people who have trouble sleeping and the mental health issues that can come with it.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Arizona
NIH-funded
Lab location1 site (Tucson, United States)
Project startDecember 27, 2024
Project endNovember 30, 2029
Funding year2025
Award (this year)$793,161
NIH project number1R01MH135978-01A1
Project IDNIH-11048053 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research include individuals under 21 years old who experience sleep disruptions and exhibit signs of emotional or cognitive dysregulation.

Less likely to help

Patients who do not experience sleep disturbances or who are not at risk for suicidal ideation may not benefit from this research.

What this research studies

This research explores the connection between nocturnal wakefulness and increased suicide risk, particularly focusing on emotional and cognitive dysregulation that can occur during these hours. By using actigraphy to monitor sleep patterns, the study aims to understand how being awake at night can lead to negative feelings and impulsive behaviors. The researchers will analyze data from various demographics to identify patterns and potential interventions that could mitigate these risks. The ultimate goal is to develop strategies to help individuals who struggle with sleep disruptions and their associated mental health challenges.

Why it matters

Potential benefit: If successful, this research could lead to improved interventions for individuals at risk of suicide due to sleep-related issues.

How similar studies have gone: Previous research has indicated a strong correlation between sleep disruption and increased suicide risk, suggesting that this approach is grounded in established findings.

Where this research is happening

  • University of Arizona
    Tucson, United States
    Active

Researchers

  • Principal investigator: Grandner, Michael a — University of Arizona
  • Study coordinator: Grandner, Michael a

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.