Investigating how SSRIs affect height growth in adolescents
Official title: Long-term Trajectory of SSRI-Induced Height Growth Suppression
Funded at Baylor College of Medicine · NIH-10944071 · Data updated 2026-11-12
This study is looking at how taking certain antidepressants called SSRIs might affect the height growth of teenagers over two years, helping doctors make better treatment choices for young people dealing with anxiety and depression.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Baylor College of Medicine NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project start | September 1, 2024 |
| Project end | June 30, 2029 |
| Funding year | 2024 |
| Award (this year) | $707,858 |
| NIH project number | 1R01HD115645-01 |
| Project ID | NIH-10944071 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adolescents aged 12 to 20 who are starting treatment with SSRIs for anxiety or depressive disorders.
✕Less likely to help
Patients who are not currently taking SSRIs or who are outside the adolescent age range may not benefit from this research.
What this research studies
This research examines the long-term effects of selective serotonin reuptake inhibitors (SSRIs) on height growth in adolescents. It focuses on understanding whether the suppression of height growth and levels of insulin growth factor 1 (IGF-1) continues over a two-year period in young patients taking SSRIs. By analyzing data from adolescents who have started treatment with SSRIs, the study aims to provide insights into the relationship between medication dosage and growth suppression. This research is crucial for informing treatment decisions for adolescents experiencing anxiety and depression.
Why it matters
Potential benefit: If successful, this research could lead to better management strategies for adolescents on SSRIs, potentially minimizing negative impacts on growth.
How similar studies have gone: Previous studies have indicated that SSRIs can suppress height growth in adolescents, suggesting that this research builds on established findings rather than exploring a completely novel approach.
Where this research is happening
-
Baylor College of Medicine
Houston, United States Active
Researchers
- Principal investigator: Calarge, Chadi a. — Baylor College of Medicine
- Study coordinator: Calarge, Chadi a.
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.