Investigating how specific proteins affect signaling in neurological diseases.

Serine/Threonine Phosphatases in Neurological Diseases

NIH-funded research University of Connecticut Sch of Med/dnt · NIH-11004985

This study is looking at how certain proteins in the brain might affect signaling and communication between nerve cells, especially in relation to Alzheimer's disease, to help find new ways to treat this condition.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Connecticut Sch of Med/dnt NIH-funded
Lab location1 site (Farmington, United States)
Project IDNIH-11004985 on NIH RePORTER

What this research studies

This research focuses on understanding the role of serine/threonine phosphatases in neuronal signaling, particularly in relation to diseases like Alzheimer's. The team will explore how these proteins interact with other molecules in neurons and how their functions may change in response to different stimuli. By identifying the specific substrates these phosphatases target, the research aims to uncover new insights into the mechanisms behind neurological disorders. This work could lead to the development of new therapeutic strategies for conditions such as Alzheimer's disease.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals diagnosed with Alzheimer's disease or those experiencing cognitive decline.

Not a fit: Patients with neurological conditions unrelated to Alzheimer's or those without cognitive impairment may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved understanding and treatment options for patients with Alzheimer's disease and other neurological disorders.

How similar studies have performed: Previous research has shown promising results in understanding neuronal signaling pathways, suggesting that this approach could yield valuable insights.

Where this research is happening

Farmington, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Alzheimer disease dementiaAlzheimer syndromeAlzheimer's Disease
Last reviewed 2026-06-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.