Investigating how specific immune cells affect high blood pressure
The Role of CCR10+ Regulatory T Cells In Hypertension
['FUNDING_CAREER'] · VANDERBILT UNIVERSITY MEDICAL CENTER · NIH-10849859
This study is looking at a special kind of immune cell that might play a part in high blood pressure, and it's for anyone interested in understanding how these cells affect blood vessels and could lead to better treatments for managing hypertension.
Quick facts
| Phase | ['FUNDING_CAREER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | VANDERBILT UNIVERSITY MEDICAL CENTER (nih funded) |
| Locations | 1 site (NASHVILLE, UNITED STATES) |
| Trial ID | NIH-10849859 on ClinicalTrials.gov |
What this research studies
This research explores the role of a specific type of immune cell, known as CCR10+ regulatory T cells, in the development of hypertension. It aims to understand how these cells interact with blood vessels and contribute to high blood pressure. By studying both human and animal models, the research seeks to uncover new therapeutic targets that could help manage hypertension more effectively. The approach includes examining the effects of increased blood pressure on these immune cells and their potential role in vascular health.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with hypertension who may not be adequately controlled with current therapies.
Not a fit: Patients with normal blood pressure or those whose hypertension is well-managed with existing treatments may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments for hypertension, improving blood pressure control and reducing the risk of cardiovascular events.
How similar studies have performed: Other research has indicated the immune system's involvement in hypertension, suggesting that this approach could yield meaningful insights and potential breakthroughs.
Where this research is happening
NASHVILLE, UNITED STATES
- VANDERBILT UNIVERSITY MEDICAL CENTER — NASHVILLE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: ALEXANDER, MATTHEW R — VANDERBILT UNIVERSITY MEDICAL CENTER
- Study coordinator: ALEXANDER, MATTHEW R
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.