Investigating how specific genes affect body weight control
The role of regulator of G protein signaling Gbeta5-R7 in neuronal control of body weight
This study is looking at how certain genes might affect body weight and contribute to obesity, and it's for anyone interested in understanding more about the causes of weight gain and potential new treatments for obesity.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Miami School of Medicine NIH-funded |
| Lab location | 1 site (Coral Gables, United States) |
| Project ID | NIH-10757037 on NIH RePORTER |
What this research studies
This research explores the role of certain genes, specifically the Gnb5 and R7 genes, in regulating body weight and how deficiencies in these genes can lead to obesity. By studying the mechanisms in which these genes operate, particularly in the brain and pancreatic cells, the research aims to uncover new insights into obesity and related metabolic disorders. The approach includes genetic analysis and functional studies in animal models, which may provide a better understanding of how these genes influence energy balance and caloric intake. Ultimately, the goal is to identify potential therapeutic targets for obesity and its associated health complications.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults over 21 years old who are struggling with obesity or related metabolic conditions.
Not a fit: Patients who are not affected by obesity or metabolic disorders may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments for obesity and related metabolic disorders, improving health outcomes for affected individuals.
How similar studies have performed: Previous research has shown promising results in understanding the genetic factors influencing obesity, suggesting that this approach could yield significant insights.
Where this research is happening
Coral Gables, United States
- University of Miami School of Medicine — Coral Gables, United States (Active)
Researchers
- Principal investigator: Slepak, Vladlen Z — University of Miami School of Medicine
- Study coordinator: Slepak, Vladlen Z
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.