Investigating how specific cells in tendons help with healing and adaptation.
Official title: Epitenon-derived progenitor cells in tendon healing and adaptation
Funded at University of Rochester · NIH-11077382 · Data updated 2026-11-12
This study is looking at special cells that help heal tendons after an injury, and it aims to find ways to use these cells to make tendons healthier, especially for people who are active or have tendon injuries.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Rochester NIH-funded |
| Lab location | 1 site (Rochester, United States) |
| Project start | July 1, 2024 |
| Project end | June 30, 2027 |
| Funding year | 2024 |
| Award (this year) | $249,000 |
| NIH project number | 4R00AR080757-03 |
| Project ID | NIH-11077382 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with acute tendon injuries or those experiencing tendon-related issues.
✕Less likely to help
Patients with chronic tendon conditions or those who do not have tendon injuries may not benefit from this research.
What this research studies
This research focuses on understanding the role of epitenon-derived progenitor cells in tendon healing and adaptation to mechanical stress. By identifying a specific population of cells that contribute to tendon repair after injury, the study aims to explore how these cells can be harnessed to improve tendon health. The researchers will utilize advanced genetic mouse models and voluntary exercise to simulate tendon growth and assess the behavior of these progenitor cells. This approach could lead to new insights into tendon biology and potential therapeutic strategies for tendon injuries.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for tendon injuries, enhancing recovery and overall tendon health.
How similar studies have gone: While the specific focus on epitenon-derived progenitor cells is novel, similar research approaches have shown promise in understanding tendon biology and healing.
Where this research is happening
-
University of Rochester
Rochester, United States Active
Researchers
- Principal investigator: Nichols, Anne E.c. — University of Rochester
- Study coordinator: Nichols, Anne E.c.
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.