Investigating how specific breathing techniques affect Alzheimer's disease biomarkers and cognition.
Effects of Resonance-Frequency Breathing on Preclinical Alzheimer’s Disease Biomarkers and Cognition
['FUNDING_R01'] · UNIVERSITY OF SOUTHERN CALIFORNIA · NIH-11085133
This study is looking at how a special breathing technique might help improve brain health and reduce a protein linked to Alzheimer's in adults aged 50-70, especially focusing on both African-American and European-American participants to better understand health differences.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF SOUTHERN CALIFORNIA (nih funded) |
| Locations | 1 site (Los Angeles, UNITED STATES) |
| Trial ID | NIH-11085133 on ClinicalTrials.gov |
What this research studies
This research explores the impact of resonance-frequency breathing on biomarkers associated with Alzheimer's disease in adults aged 50-70. Participants will engage in daily breathing sessions over ten weeks, with some practicing resonance-frequency breathing and others using different techniques. The study aims to understand how these breathing methods influence levels of beta-amyloid, a protein linked to Alzheimer's, and cognitive function. By focusing on both African-American and European-American adults, the research seeks to address health disparities in Alzheimer's disease.
Who could benefit from this research
Good fit: Ideal candidates for this research are healthy adults aged 50-70, particularly those interested in cognitive health and Alzheimer's prevention.
Not a fit: Patients with advanced Alzheimer's disease or significant cognitive impairment may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to non-invasive, cost-effective interventions that help prevent or delay the onset of Alzheimer's disease.
How similar studies have performed: Previous studies have shown promising results with breathing techniques affecting biomarkers in other health conditions, suggesting potential for success in this novel application.
Where this research is happening
Los Angeles, UNITED STATES
- UNIVERSITY OF SOUTHERN CALIFORNIA — Los Angeles, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: MATHER, MARA — UNIVERSITY OF SOUTHERN CALIFORNIA
- Study coordinator: MATHER, MARA
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Acquired brain injury