Investigating how specific brain neurons affect chronic pain

Neuropeptide Y1 Receptor-Expressing Neurons in the Lateral Parabrachial Nucleus in Neuropathic Pain

NIH-funded research University of Florida · NIH-11076040

This study is looking at how certain brain cells that help process pain might be involved in chronic pain conditions, with the hope of finding new ways to help people manage their pain better.

Quick facts

Grant typeFellowship grant
Study typeNIH-funded research
Funding institutionUniversity of Florida NIH-funded
Lab location1 site (Gainesville, United States)
Project IDNIH-11076040 on NIH RePORTER

What this research studies

This research focuses on understanding the role of neuropeptide Y1 receptor-expressing neurons in the lateral parabrachial nucleus, a brain region involved in pain processing. By examining how these neurons contribute to neuropathic pain, the study aims to uncover new therapeutic targets for patients suffering from chronic pain conditions. The approach includes advanced neurobiological techniques to analyze neuronal activity and its effects on pain perception. Patients may benefit from insights that could lead to more effective pain management strategies.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals experiencing neuropathic pain that has not responded well to traditional analgesic treatments.

Not a fit: Patients with acute pain or those whose pain is not neuropathic in nature may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to new treatments for chronic pain that are more effective than current options.

How similar studies have performed: Other research has shown promise in targeting specific brain regions for pain management, suggesting that this approach could yield significant insights.

Where this research is happening

Gainesville, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.