Investigating how specific astrocyte factors contribute to brain inflammation
Official title: Functional interrogation of region-specific reactive astrocyte factors in neuroinflammation
Funded at New York University School of Medicine · NIH-10997906 · Data updated 2026-11-12
This study is looking at how a special type of brain cell called astrocytes responds to inflammation, which could help us find new ways to treat brain diseases that involve inflammation, so it’s important for anyone affected by these conditions.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | New York University School of Medicine NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | July 1, 2024 |
| Project end | June 30, 2026 |
| Funding year | 2024 |
| Award (this year) | $41,906 |
| NIH project number | 1F31NS135948-01A1 |
| Project ID | NIH-10997906 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals experiencing neurological conditions that involve neuroinflammation.
✕Less likely to help
Patients with non-neurological conditions or those not affected by neuroinflammation may not benefit from this research.
What this research studies
This research focuses on understanding the role of astrocytes, a type of brain cell, in the immune response during neuroinflammation. By using advanced techniques like ATAC sequencing, the study examines how these cells react to inflammation in different regions of the brain. The goal is to uncover the diverse responses of astrocytes to inflammatory signals, which could lead to better insights into brain diseases. Patients may benefit from this research as it aims to identify new therapeutic targets for conditions involving neuroinflammation.
Why it matters
Potential benefit: If successful, this research could lead to new treatments for brain diseases associated with inflammation.
How similar studies have gone: Other research has shown promising results in understanding astrocyte functions in neuroinflammation, indicating that this approach has potential for success.
Where this research is happening
-
New York University School of Medicine
New York, United States Active
Researchers
- Principal investigator: O'dea, Michael Ryan — New York University School of Medicine
- Study coordinator: O'dea, Michael Ryan
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.