NIH-funded research NIH-funded research

Investigating how social and dietary factors affect kidney stone risk

Official title: Social and Dietary Determinants of Kidney Stone Risk

Funded at University of Alabama at Birmingham · NIH-11049094 · Data updated 2026-11-12

This study looks at how things like where you live and your eating habits can affect your chances of getting kidney stones, especially for Black and Hispanic communities, and it hopes to find ways to suggest better diets to help lower that risk.

More Kidney Stone research and trials

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of Alabama at Birmingham
NIH-funded
Lab location1 site (Birmingham, United States)
Project startMay 25, 2023
Project endFebruary 29, 2028
Funding year2025
Award (this year)$182,101
NIH project number5K23DK135844-03
Project IDNIH-11049094 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research include individuals from racially and ethnically diverse backgrounds, particularly Black and Hispanic adults, who are at risk for kidney stone disease.

Less likely to help

Patients who do not belong to the targeted racial and ethnic groups or those who do not have risk factors for kidney stones may not benefit from this research.

What this research studies

This research explores the relationship between social determinants of health and dietary habits on the risk of developing kidney stones, particularly in racially and ethnically diverse populations. It aims to identify specific risk factors and how changes in diet can influence kidney stone prevalence. By analyzing data from multiple studies, the research seeks to understand the impact of lifestyle and social factors on kidney stone disease, which is increasingly affecting Black and Hispanic individuals. The findings could lead to targeted dietary recommendations to reduce kidney stone risk.

Why it matters

Potential benefit: If successful, this research could provide insights that help reduce the incidence of kidney stones through improved dietary guidelines tailored to at-risk populations.

How similar studies have gone: Previous research has indicated that dietary and social factors significantly influence kidney stone risk, suggesting that this approach has the potential for meaningful insights.

Where this research is happening

  • University of Alabama at Birmingham
    Birmingham, United States
    Active

Researchers

  • Principal investigator: Crivelli, Joseph James — University of Alabama at Birmingham
  • Study coordinator: Crivelli, Joseph James

Related research

Other NIH-funded projects on the same topics.

  • Uromodulin and peptides as new targets in kidney stone biology

    This NIH grant explores how a urine protein called uromodulin and its peptide pieces influence calcium oxalate kidney stones, using dogs and human biology to understand why stones form and how to prevent them.

    NIH research University of Minnesota · Minneapolis, United States · NIH-11433374

  • Oxalate‑eating probiotic to help prevent kidney stones

    A new probiotic strain is being developed to help prevent calcium oxalate kidney stones by breaking down oxalic acid in the gut.

    NIH research Unlocked Labs INC. · Laramie, United States · NIH-11364194

  • Oxalate and your immune system in kidney stones

    This grant looks at how oxalate in our diet affects kidney stone risk and our immune cells, especially in adults with calcium oxalate stones.

    NIH research University of Alabama at Birmingham · Birmingham, United States · NIH-11359754

  • How the kidney channel claudin‑2 affects calcium balance and calcium kidney stones

    This project looks at how a kidney channel called claudin‑2 helps keep calcium from building up and forming calcium kidney stones.

    NIH research University of Kansas Medical Center · Kansas City, United States · NIH-11296431

  • Oxalate balance in people with calcium oxalate kidney stones

    This project will find out why some adults make or absorb extra oxalate that increases the chance of calcium oxalate kidney stones.

    NIH research University of Alabama at Birmingham · Birmingham, United States · NIH-11232375

  • A Probiotic to Prevent Kidney Stones

    This project is developing a new probiotic to help people prevent kidney stones by breaking down a key substance called oxalic acid.

    NIH research Unlocked Labs INC. · Laramie, United States · NIH-11170575

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.