NIH-funded research Career grant

Investigating how social and cognitive factors affect aging in autistic individuals

Official title: Social, Cognitive, and Behavioral Influences on Early Life Aging in Autism

Funded at University of California Los Angeles · NIH-10892186 · Data updated 2026-11-12

This study is looking at how different social and personal factors affect aging in people with autism, and it aims to find clues in their DNA that could help us understand their health as they get older, so we can find ways to support them better throughout their lives.

More Aging research and trials

Quick facts

Grant typeCareer grant
Study typeNIH-funded research
Funding institutionUniversity of California Los Angeles
NIH-funded
Lab location1 site (Los Angeles, United States)
Project startAugust 5, 2022
Project endJuly 31, 2027
Funding year2024
Award (this year)$182,068
NIH project number5K01MH128612-03
Project IDNIH-10892186 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research include autistic individuals, particularly those in midlife, who may be at risk for cognitive and health declines.

Less likely to help

Patients who do not have autism spectrum disorder or those who are not in the midlife age range may not benefit from this research.

What this research studies

This research focuses on understanding how social, cognitive, and behavioral influences impact the aging process in individuals with autism spectrum disorder (ASD). It aims to identify biological markers of aging through advanced techniques that analyze DNA methylation patterns, which may indicate risks for health declines as autistic individuals age. By studying these markers, the research seeks to uncover the relationship between early life experiences and later life health outcomes, potentially allowing for early interventions. The study will also explore how variations in these biological markers correlate with brain aging indicators.

Why it matters

Potential benefit: If successful, this research could lead to early identification of autistic individuals at risk for adverse health outcomes, enabling timely interventions to improve their quality of life.

How similar studies have gone: Previous research has shown promise in using biological markers to predict health outcomes in aging populations, suggesting that this approach may yield valuable insights for autistic individuals as well.

Where this research is happening

  • University of California Los Angeles
    Los Angeles, United States
    Active

Researchers

  • Principal investigator: Dickinson, Abigail H — University of California Los Angeles
  • Study coordinator: Dickinson, Abigail H

Related research

Other NIH-funded projects on the same topics.

  • Healthy aging for adults on the autism spectrum

    This project follows autistic and non-autistic adults over time to learn how physical health, mental health, thinking skills, and the brain change with age.

    NIH research University of Wisconsin-Madison · Madison, United States · NIH-11117170

  • Investigating how autism risk genes affect cognitive aging in autistic adults

    This study is looking at how certain genes linked to autism might affect memory and brain aging in autistic adults over 21, and it wants to see if there are differences between men and women in this process.

    NIH research Arizona State University-Tempe Campus · Tempe, United States · NIH-10997692

  • Understanding healthy aging in adults with autism

    This study is looking at how getting older affects adults with autism by tracking their health and brain changes over time, and it includes both autistic and non-autistic people to see what helps or hinders their well-being as they age.

    NIH research University of Wisconsin-Madison · Madison, United States · NIH-10875412

  • Neural roots of how autistic adults understand word meaning

    A study to understand how adults with autism process word meanings in the brain, aiming to improve language support.

    NIH research Ut Southwestern Medical Center · Dallas, United States · NIH-11640092

  • Aging Well with HIV: Alcohol, Risk Reduction, and Education Center (AWAR3E)

    A center at Yale is exploring how aging with HIV interacts with alcohol use to create inflammation and frailty, with the goal of finding biomarkers and potential treatments.

    NIH research Yale University · New Haven, United States · NIH-11638490

  • Cognitive SuperAging: Exploring why some octogenarians stay sharp in memory

    This NIH grant studies why a small group of people aged 80+ keep memory skills as good as much younger people, hoping to understand how to protect memory as we age.

    NIH research University of Chicago · Chicago, United States · NIH-11623260

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.