Investigating how smoking affects anxiety and body-brain communication

Smoking-related Differences in Baroreflex Sensitivity and Fear Inhibition in Adults Who Do and Do Not Smoke Cigarettes

NIH-funded research Rutgers, the State Univ of N.j. · NIH-10831828

This study is looking at how smoking might affect anxiety and the way your body responds to stress, and it's for adults who smoke or don’t smoke; you'll take part in a lab visit where you'll do a task that tests your fear responses while we check your heart rate and blood pressure.

Quick facts

Grant typeFellowship grant
Study typeNIH-funded research
Funding institutionRutgers, the State Univ of N.j. NIH-funded
Lab location1 site (Piscataway, United States)
Project IDNIH-10831828 on NIH RePORTER

What this research studies

This research explores the relationship between smoking, anxiety, and physiological responses in adults. It aims to understand how cigarette use may impair the baroreflex, a critical feedback mechanism that helps regulate communication between the body and brain. Participants will undergo a laboratory visit where they will engage in a fear conditioning task while their baroreflex function is monitored through heart rate and blood pressure measurements. The study will compare responses between smokers and non-smokers to identify potential differences in anxiety-related behaviors.

Who could benefit from this research

Good fit: Ideal candidates for this research are adults aged 21 and older who either smoke cigarettes or do not smoke.

Not a fit: Patients who are under 21 years old or those who do not have any history of smoking may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved interventions for smokers with anxiety, enhancing their chances of quitting and reducing tobacco-related health issues.

How similar studies have performed: While the specific focus on baroreflex sensitivity in relation to smoking and anxiety is relatively novel, previous studies have shown that physiological mechanisms can significantly impact anxiety and smoking cessation outcomes.

Where this research is happening

Piscataway, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.