Investigating how sleep and circadian rhythms affect treatment outcomes for opioid use disorder
Sleep and circadian rhythm phenotypes and mechanisms associated with opioid use disorder treatment outcomes
This study is looking at how sleep and body clock patterns affect the success of treatments for people recovering from opioid use disorder, and it’s for anyone receiving buprenorphine or methadone to help them on their journey to recovery.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project ID | NIH-10931450 on NIH RePORTER |
What this research studies
This research explores the relationship between sleep patterns, circadian rhythms, and the effectiveness of treatments for opioid use disorder (OUD). By enrolling participants undergoing buprenorphine or methadone treatment, the study will track their sleep quality and patterns over six months. The goal is to identify how disturbances in sleep and circadian rhythms may influence the likelihood of relapse to opioid use. This observational study aims to uncover potential pathways that could lead to improved treatment strategies for individuals struggling with OUD.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals currently receiving treatment for opioid use disorder with buprenorphine or methadone.
Not a fit: Patients who are not currently undergoing treatment for opioid use disorder may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to enhanced treatment approaches that improve recovery outcomes for patients with opioid use disorder.
How similar studies have performed: Previous research has indicated that addressing sleep disturbances can positively impact treatment outcomes for substance use disorders, suggesting a promising avenue for this study.
Where this research is happening
Baltimore, United States
- Johns Hopkins University — Baltimore, United States (Active)
Researchers
- Principal investigator: Huhn, Andrew S — Johns Hopkins University
- Study coordinator: Huhn, Andrew S
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.