NIH-funded research Fellowship grant

Investigating how sleep affects depression and suicidality related to the menstrual cycle

Official title: Sleep as a Mechanism of Premenstrual Exacerbation of Depression and Suicidality

Funded at University of Illinois at Chicago · NIH-10997175 · Data updated 2026-11-12

This study is looking at how sleep patterns can affect depression and suicidal thoughts in women, especially during their menstrual cycles, and it aims to find ways to help women feel better by understanding these connections.

More Depression research and trials

Quick facts

Grant typeFellowship grant
Study typeNIH-funded research
Funding institutionUniversity of Illinois at Chicago
NIH-funded
Lab location1 site (Chicago, UNITED STATES)
Project startJune 27, 2024
Project endJune 26, 2028
Funding year2024
Award (this year)$53,974
NIH project number1F30MH138058-01
Project IDNIH-10997175 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are women who experience depression and suicidal thoughts that fluctuate with their menstrual cycles.

Less likely to help

Patients who do not experience menstrual cycles or who have stable mental health without fluctuations related to hormonal changes may not benefit from this research.

What this research studies

This research explores the relationship between sleep patterns and the exacerbation of depression and suicidality in women, particularly in relation to their menstrual cycles. By utilizing advanced digital health technologies to gather detailed sleep data, the study aims to identify critical periods when women may be at higher risk for suicidal thoughts and behaviors. The research also seeks to uncover potential treatment targets that could mitigate these risks, focusing on the hormonal changes that occur during the menstrual cycle. Participants may be involved in clinical trials that assess these dynamics and their implications for mental health.

Why it matters

Potential benefit: If successful, this research could lead to improved strategies for preventing suicidality and managing depression in women, particularly during vulnerable times in their menstrual cycles.

How similar studies have gone: Previous research has shown promising results in understanding the link between hormonal changes and mental health, suggesting that this approach could yield valuable insights.

Where this research is happening

  • University of Illinois at Chicago
    Chicago, United States
    Active

Researchers

  • Principal investigator: Nagpal, Anisha — University of Illinois at Chicago
  • Study coordinator: Nagpal, Anisha

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.