Investigating how sleep affects depression and suicidality related to the menstrual cycle

Sleep as a Mechanism of Premenstrual Exacerbation of Depression and Suicidality

NIH-funded research University of Illinois at Chicago · NIH-10997175

This study is looking at how sleep patterns can affect depression and suicidal thoughts in women, especially during their menstrual cycles, and it aims to find ways to help women feel better by understanding these connections.

Quick facts

Grant typeFellowship grant
Study typeNIH-funded research
Funding institutionUniversity of Illinois at Chicago NIH-funded
Lab location1 site (Chicago, UNITED STATES)
Project IDNIH-10997175 on NIH RePORTER

What this research studies

This research explores the relationship between sleep patterns and the exacerbation of depression and suicidality in women, particularly in relation to their menstrual cycles. By utilizing advanced digital health technologies to gather detailed sleep data, the study aims to identify critical periods when women may be at higher risk for suicidal thoughts and behaviors. The research also seeks to uncover potential treatment targets that could mitigate these risks, focusing on the hormonal changes that occur during the menstrual cycle. Participants may be involved in clinical trials that assess these dynamics and their implications for mental health.

Who could benefit from this research

Good fit: Ideal candidates for this research are women who experience depression and suicidal thoughts that fluctuate with their menstrual cycles.

Not a fit: Patients who do not experience menstrual cycles or who have stable mental health without fluctuations related to hormonal changes may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved strategies for preventing suicidality and managing depression in women, particularly during vulnerable times in their menstrual cycles.

How similar studies have performed: Previous research has shown promising results in understanding the link between hormonal changes and mental health, suggesting that this approach could yield valuable insights.

Where this research is happening

Chicago, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.