Investigating how sleep affects depression and suicidal thoughts in teenagers

Longitudinal study of sleep duration, reward and cognitive control circuits, and vulnerability for depression and suicidal ideation during adolescence

NIH-funded research University of Pittsburgh at Pittsburgh · NIH-10669578

This study is looking at how not getting enough sleep might affect the mental health of kids aged 11 to 14, especially in relation to feelings of sadness and thoughts about suicide, by tracking their sleep habits and mental well-being over the school year.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Pittsburgh at Pittsburgh NIH-funded
Lab location1 site (Pittsburgh, United States)
Project IDNIH-10669578 on NIH RePORTER

What this research studies

This research explores the relationship between sleep duration and mental health in adolescents, particularly focusing on how insufficient sleep may contribute to depression and suicidal ideation. By examining brain activity related to reward and cognitive control, the study aims to understand the impact of sleep loss on these critical neural pathways. The research will involve a longitudinal approach, tracking a group of 210 youths aged 11.5 to 14.5 over time to assess changes in their mental health as it relates to their sleep patterns during the school year.

Who could benefit from this research

Good fit: Ideal candidates for this research are adolescents aged 11.5 to 14.5 who experience varying sleep durations, particularly those who typically sleep 7 hours or less.

Not a fit: Patients outside the age range of 11.5 to 14.5 or those who do not experience sleep issues may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved strategies for preventing and treating depression and suicidal thoughts in adolescents by addressing sleep issues.

How similar studies have performed: Previous research has shown promising results in understanding the link between sleep and mental health, suggesting that this approach could yield valuable insights.

Where this research is happening

Pittsburgh, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.