NIH-funded research R01 grant

Investigating how skin color affects pulse oximeter accuracy in children

Official title: Evaluating the relationship between skin color and pulse oximeter accuracy in children

Funded at University of Pennsylvania · NIH-11002312 · Data updated 2026-11-12

This study is looking at how well pulse oximeters, which check blood oxygen levels, work for kids with different skin colors during a heart procedure, to make sure all children get the best care possible.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Pennsylvania
NIH-funded
Lab location1 site (Philadelphia, United States)
Project startJanuary 1, 2024
Project endDecember 31, 2028
Funding year2025
Award (this year)$450,924
NIH project number5R01HL171313-02
Project IDNIH-11002312 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are children under 18 years old who are scheduled for cardiac catheterization.

Less likely to help

Patients who are not undergoing cardiac catheterization or are over 18 years old may not benefit from this research.

What this research studies

This research aims to understand how the accuracy of pulse oximeters, which are crucial for monitoring blood oxygen levels in children, may vary based on skin color. The study will involve children under 18 years old who are undergoing cardiac catheterization, a procedure that requires precise monitoring of oxygen saturation. By using objective measures of skin color, the researchers hope to identify any discrepancies in pulse oximeter readings, particularly for children with darker skin tones. The findings could lead to improved clinical practices and policies regarding the use of pulse oximeters in pediatric care.

Why it matters

Potential benefit: If successful, this research could lead to more accurate monitoring of blood oxygen levels in children, particularly those with darker skin, improving their overall care and outcomes.

How similar studies have gone: Previous studies have indicated potential inaccuracies in pulse oximeter readings based on skin color, but this research specifically focuses on children, making it a novel approach.

Where this research is happening

  • University of Pennsylvania
    Philadelphia, United States
    Active

Researchers

  • Principal investigator: Ruppel, Halley — University of Pennsylvania
  • Study coordinator: Ruppel, Halley

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.