Investigating how sex hormones affect stroke risk
Official title: The Role of Sex Hormones in Stroke Risk: A Sex-Specific Integrative Omics Analysis in the NHLBI Trans-Omics for Precision Medicine Cohorts
Funded at Rhode Island Hospital · NIH-10916361 · Data updated 2026-11-12
This study is looking at how sex hormones affect the risk of having a stroke, so we can create better prevention strategies for both men and women to help reduce the chances of strokes and their serious effects.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Rhode Island Hospital NIH-funded |
| Lab location | 1 site (Providence, United States) |
| Project start | September 1, 2023 |
| Project end | July 31, 2028 |
| Funding year | 2024 |
| Award (this year) | $683,983 |
| NIH project number | 5R01HL164485-02 |
| Project ID | NIH-10916361 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include both men and women who are at risk of stroke or have a family history of stroke.
✕Less likely to help
Patients who have already experienced a stroke or those with conditions unrelated to stroke risk may not benefit from this research.
What this research studies
This research explores the impact of sex hormones on stroke risk, aiming to personalize prevention strategies based on these differences. By analyzing existing data from diverse populations, the study seeks to identify specific biological markers and mechanisms that contribute to stroke risk in men and women. The research team will develop sex-specific risk scores to improve prediction and prevention of strokes, ultimately aiming to reduce stroke-related deaths and disabilities.
Why it matters
Potential benefit: If successful, this research could lead to more effective, personalized stroke prevention strategies tailored to individual hormonal profiles.
How similar studies have gone: Previous research has shown promising results in understanding sex differences in stroke risk, indicating that this approach could yield valuable insights.
Where this research is happening
-
Rhode Island Hospital
Providence, United States Active
Researchers
- Principal investigator: Madsen, Tracy — Rhode Island Hospital
- Study coordinator: Madsen, Tracy
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.