Investigating how sex hormones affect stroke risk
The Role of Sex Hormones in Stroke Risk: A Sex-Specific Integrative Omics Analysis in the NHLBI Trans-Omics for Precision Medicine Cohorts
['FUNDING_R01'] · RHODE ISLAND HOSPITAL · NIH-10916361
This study is looking at how sex hormones affect the risk of having a stroke, so we can create better prevention strategies for both men and women to help reduce the chances of strokes and their serious effects.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | RHODE ISLAND HOSPITAL (nih funded) |
| Locations | 1 site (PROVIDENCE, UNITED STATES) |
| Trial ID | NIH-10916361 on ClinicalTrials.gov |
What this research studies
This research explores the impact of sex hormones on stroke risk, aiming to personalize prevention strategies based on these differences. By analyzing existing data from diverse populations, the study seeks to identify specific biological markers and mechanisms that contribute to stroke risk in men and women. The research team will develop sex-specific risk scores to improve prediction and prevention of strokes, ultimately aiming to reduce stroke-related deaths and disabilities.
Who could benefit from this research
Good fit: Ideal candidates for this research include both men and women who are at risk of stroke or have a family history of stroke.
Not a fit: Patients who have already experienced a stroke or those with conditions unrelated to stroke risk may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective, personalized stroke prevention strategies tailored to individual hormonal profiles.
How similar studies have performed: Previous research has shown promising results in understanding sex differences in stroke risk, indicating that this approach could yield valuable insights.
Where this research is happening
PROVIDENCE, UNITED STATES
- RHODE ISLAND HOSPITAL — PROVIDENCE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: MADSEN, TRACY — RHODE ISLAND HOSPITAL
- Study coordinator: MADSEN, TRACY
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Cardiovascular Diseases