Investigating how sex differences in vasopressin affect social behavior
Sexually Dimorphic Vasopressin Circuits in the Control of Social Interest
['FUNDING_R01'] · GEORGIA STATE UNIVERSITY · NIH-10980228
This study is looking at how a brain chemical called arginine vasopressin affects social behavior differently in men and women, and it aims to help us understand social behavior disorders better.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | GEORGIA STATE UNIVERSITY (nih funded) |
| Locations | 1 site (ATLANTA, UNITED STATES) |
| Trial ID | NIH-10980228 on ClinicalTrials.gov |
What this research studies
This research explores the role of the neuropeptide arginine vasopressin (AVP) in social behavior, particularly focusing on how its effects differ between sexes. By examining specific brain regions involved in social interest, the study aims to understand the mechanisms behind these differences. Researchers will utilize advanced techniques such as optogenetics to manipulate brain activity and assess changes in behavior and cellular function. The goal is to uncover how AVP influences social interactions in adults, which could lead to better understanding of social behavior disorders.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults with social behavior disorders, particularly those diagnosed with autism spectrum disorder (ASD).
Not a fit: Patients who do not have social behavior disorders or those outside the age range of 21 years and older may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new insights and treatments for social behavior disorders, particularly those that exhibit sex differences.
How similar studies have performed: While the specific approach of examining AVP's role in social behavior is relatively novel, there is existing research indicating that neuropeptides can significantly influence social behaviors.
Where this research is happening
ATLANTA, UNITED STATES
- GEORGIA STATE UNIVERSITY — ATLANTA, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: PETRULIS, ARAS T — GEORGIA STATE UNIVERSITY
- Study coordinator: PETRULIS, ARAS T
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Autistic Disorder