Investigating how sex differences affect stroke imaging and treatment decisions

Acute Ischemic Tissue Evolution and Implications for Imaging Selection of Patients for Therapy and Clinical Trials using Sex-Disaggregated Data

NIH-funded research University of Texas at Austin · NIH-10575791

This study is looking at how men and women experience strokes differently, especially in how they are diagnosed and treated, to help improve care and outcomes for everyone affected by strokes.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionUniversity of Texas at Austin NIH-funded
Lab location1 site (Austin, United States)
Project IDNIH-10575791 on NIH RePORTER

What this research studies

This research focuses on understanding how acute ischemic stroke affects men and women differently, particularly in terms of imaging and treatment options. It aims to identify the evolution of ischemic tissue in both sexes to improve personalized imaging selection for therapy and clinical trials. By analyzing sex-disaggregated data, the study seeks to address the disparities in treatment outcomes and optimize care for stroke patients. The research will explore why women, despite presenting with more favorable imaging profiles, often experience worse functional outcomes after a stroke.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals who have experienced an acute ischemic stroke, with a focus on both men and women.

Not a fit: Patients who have not experienced an acute ischemic stroke or those with other types of strokes may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved imaging techniques and treatment strategies for stroke patients, particularly benefiting women.

How similar studies have performed: While there is ongoing research into sex differences in stroke, this specific approach focusing on imaging and treatment selection using sex-disaggregated data is relatively novel.

Where this research is happening

Austin, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.