Investigating how sex differences affect recovery from sub-cortical stroke.
Official title: Sex differences and spreading depolarization preconditioning in sub-cortical stroke
Funded at University of New Mexico Health Scis Ctr · NIH-11262745 · Data updated 2026-11-12
This study is looking at how men and women recover from strokes differently, especially focusing on younger patients, to see how female hormones might help with healing and preventing future strokes, all while using new technology to check brain function.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of New Mexico Health Scis Ctr NIH-funded |
| Lab location | 1 site (Albuquerque, United States) |
| Project start | January 22, 2025 |
| Project end | June 30, 2026 |
| Funding year | 2024 |
| Award (this year) | $145,058 |
| NIH project number | 5P20GM109089-10 |
| Project ID | NIH-11262745 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include younger stroke survivors, particularly women, who are experiencing or at risk for recurrent strokes.
✕Less likely to help
Patients who have not experienced a stroke or those with non-ischemic stroke types may not benefit from this research.
What this research studies
This research explores how sex differences influence the recovery and resilience of stroke survivors, particularly focusing on the effects of spreading depolarization in the brain. It aims to understand how these processes differ between males and females, especially in younger stroke patients who may face unique challenges. By examining the role of female sex hormones in promoting recovery and preventing recurrent strokes, the study utilizes advanced technological methods to assess brain function in areas beyond the immediate stroke site. The goal is to identify potential protective mechanisms that could improve outcomes for stroke survivors.
Why it matters
Potential benefit: If successful, this research could lead to new treatment strategies that enhance recovery and reduce the risk of recurrent strokes, particularly in younger women.
How similar studies have gone: While there has been some research on sex differences in stroke recovery, this specific approach focusing on spreading depolarization in sub-cortical areas is relatively novel.
Where this research is happening
-
University of New Mexico Health Scis Ctr
Albuquerque, United States Active
Researchers
- Principal investigator: Boyce, Andrew — University of New Mexico Health Scis Ctr
- Study coordinator: Boyce, Andrew
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.